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Progestin Bioidentical Hormones
About Progestin

A Progestin is a synthetic progestogen, that has progestinic effects similar to progesterones. The two most common uses of progestins are for hormonal contraception (either alone or with an estrogen) & to prevent endometrial hyperplasia from unopposed estrogen in hormone replacement therapy. Progestins are also used to treat secondary menorrhea, dysfunctional uterine bleeding, endometriosis, & as a palliative treatment of endometrial cancer, renal cell carcinoma, breast cancer, & prostate cancer. High-dose megestrol acetate is used to treat anorexia, cachexia, & AIDS related wasting. They are also used in judicial chemical castration of the sex offenders as well as a treatment options for those suffering from paraphilia. Progestins are not used routinely in Age Management Medicine & Boo-identical hormone replacement programs, however, their side effects routinely are misattributed to progesterone & estrogen.
Adverse Effects of Progestins
  • Acne
  • Changes in menstrual flow
  • Drowsiness
  • Birth defects if taken by pregnant women
  • Breast infections
  • Increased facial hair
  • Decreased scalp hair
  • Difficulty falling or remaining asleep
  • Stomach pain
  • Weight gain
  • Worsening of diabetes mellitus
  • Edema (particularly of the face)
  • Thrombosis
  • Painful urnination
  • Anxiety
  • Headaches
  • Nausea with vomiting
  • Decreased libido
  • Male impotence
  • Reduced ejacualation volume
  • Chemical castration within 3 days
  • Bone density reduction
  • Adrenal gland supression
  • Insulin resistance
  • Increased risk of breast cancer
  • Increased risk of vascular dementia
  • Increased risk of cardiovascular disease & stroke
Some examples of progestins that have been used in hormonal contraceptives and HRT are norethynodrel (Enovid), norethindrone (many brand names, most notably Ortho-Novum and Ovcon), norgestimate (ortho Tricyclen, Othro-Cyclen), norgestrel, levonorgestrel (Alesse, Trivora-28, Plan B, Mirena), medroxyprogesterone (Provera, Depo-Provera, Prempro), desogestrel, etonogestrel (Nexplanon), and drospirenone (Yasmin, Yasminelle, YAZ).
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*DISCLAIMER: The information provided on this website is intended for educational purposes only. The educational material contained in this site is based on readily available information and the experience of Forever Ageless Age Management and Bioidentical HRT. This information is not intended to self diagnose any conditions or treatments and it is recommended that you seek a professional's opinion. This information is not intended to diagnose, treate or prevent any disease.