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Estrogen Bioidentical Hormones
About Estrogen

Estrogens are a group of compounds named for their importance in the estrogen cycle of humans. The three major naturally occurring estrogens in women are estrone (E1), estradiol (E2), and estriol (E3). Estradiol is the predominant estrogen during the reproductive years, both in terms of absolute serum levels, as well as in terms of estrogenic activity. During menopause, estrone is the predominant circulating estrogen, while during pregnancy estriol is the predominant circulating estrogen in terms of serum levels. Although estriol is the most plentiful of the three estrogens, it is also the weakest, whereas estradiol is the strongest, with a potency of approximately 80 times that of estriol. Another type of estrogen called estetrol (E4) is produced only during pregnancy. All of the different forms of estrogen are synthesized from androgens, specifically testosterone and androstenedione by the enzyme aromatase.
What we do at Forever Ageless

Estrogen and progesterone applied orally, transvaginally, sublingually, or transdermally have a different spectrum of side-effects and biological outcomes. The determination of optimal preparation, dose, method, and route of administration for each individual patient is the essence and art of age management. Our protocols are highly individualized in order to maximize benefits and minimize even the theoretical side effects.
Why Optimize Estrogen Levels with Bioidentical Hormone Replacement Therapy
    Positive Health Effects of Estrogen

  • Promotes formation of female secondary sex characteristics
  • Accelerates metabolism
  • Stimulates endometrial growth
  • Increases uterine growth
  • Increases breast growth
  • Increases vaginal lubrication
  • Thickens vaginal wall
  • Maintains vessel and skin health
  • Reduces bone resorption and increases bone formation
  • increases hepatic production of binding proteins including SHBG
  • Increases HDL and triglycerides and decreases LDL cholesterol
  • Increases salt and water retention
  • Reduces bowel motility
  • Increases cholesterol secretion in bile
  • Promotes lung function by supporting alveoli
  • Promotes sexual receptivity and induces lordosis behavior which is regulated by the ventromedial nucleus of the hypothalamus
  • Regulates libido - The sex drive is dependent on androgen levels only in the presence of estrogen, but without estrogen, testosterone levels actually decrease sexual desire (instead of increasing sex drive), as demonstrated by women who have hypoactive sexual desire disorder
    Clinical Implications
    Synthetic estrogens along with synthetic progestins are widely used in oral contraceptives. Estrogens can also be used to suppress lactation after child birth.

      Bioidentical Hormone Replacement Therapy with Estradiol (E2) In Combination with Progesterone (P4) has been shown to:

        Decrease the risk of developing:
      • Metabolic syndrome
      • Insulin resistance
      • Osteoporosis
      • Vascular dementia and Alzheimer' disease
      • Macular degeneration
      • Atherosclerosis: lowers LDL andtriglycerides, raises HDL levels and has endothelial vasodilatation properties plus and anti-inflammatory component
      • Diabetes mellitus
      • Colon cancer
      • Weight gain
      • Urinary tract infections (UTIs)

        Effectively Treat The Following:
      • Symptoms of menopause
      • Skin atrophy, wrinkling and thinning
      • Hot flashes
      • Vaginal dryness
      • Vaginal atrophy
      • Urinary and fecal stress incontinence
      • Chilly sensations
      • Dizziness
      • Fatigue
      • Irritability
      • Sweating
      • "Mental Fog"
      • Insomnia
      • Anxiety and panic attacks
      • Postpartum, perimenopausal and postmenopausal depressions
      • obsessive-compulsive disorder (OCD)
      • estradiol alone may also be used in males for treatment of prostate cancer

      Side Effects
      Prolonged unopposed estradiol (E2) without concomitant use of progesterone (P4) therapy is known to increase the risk of endometrial cancer. Conjugated equine estrogens and other synthetic estrogens have increased risks of dangerous blood clotting, heart attack, stroke, and vascular dementia, and breast cancer especially when combined with synthetic progestins.
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*DISCLAIMER: The information provided on this website is intended for educational purposes only. The educational material contained in this site is based on readily available information and the experience of Forever Ageless Age Management and Bioidentical HRT. This information is not intended to self diagnose any conditions or treatments and it is recommended that you seek a professional's opinion. This information is not intended to diagnose, treate or prevent any disease.